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2287

抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
T18639	Cl-C6-PEG4-O-CH2COOH PROTAC Linker 4	Others	Others
	Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) 是一种有效的基于聚乙二醇的 PROTAC 连接剂，常被用于 PROTAC 合成氯烷(HaloPROTACs)。
T18629	PEG3-O-CH2COOH PROTAC Linker 8,三聚乙二醇-乙酸	Others; PROTAC Linker	Others; PROTAC
	PEG3-O-CH2COOH (PROTAC Linker 8) 是一种属于 PEG 类的 PROTAC linker，可用于 SNIPER 分子的合成。
T18616	NH2-C2-NH-Boc PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺	Others; PROTAC Linker	Others; PROTAC
	NH2-C2-NH-Boc (PROTAC Linker 22) 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T18617	NH2-C5-NH-Boc N-(5-氨基戊基)氨基甲酸叔丁酯,PROTAC Linker 23	Others; PROTAC Linker	Others; PROTAC
	NH2-C5-NH-Boc (PROTAC Linker 23) 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T7701	Boc-NH-PEG3 PROTAC Linker 10,2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇	Others; PROTAC Linker	Others; PROTAC
	Boc-NH-PEG3 (PROTAC Linker 10) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 的合成分子。
T18614	Bis-Tos-PEG4 Tetraethylene glycol di(p-toluenesulfonate),PROTAC Linker 16,1,11-Bis(tosyloxy)-3,6,9-trioxaundecane	Others; PROTAC Linker	Others; PROTAC
	Bis-Tos-PEG4 (PROTAC Linker 16) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T18363	Monoethyl pimelate	Others; PROTAC Linker	Others; PROTAC
	Monoethyl pimelate 是一种属于 alkyl/ether 类的 PROTAC linker 可用于特异性的 BCL-XLPROTAC 降解剂 (S,R,S)-AHPC-Me-C7 ester 的合成。
T18788	tert-Butyl 11-aminoundecanoate	PROTAC Linker	PROTAC
	tert-Butyl 11-aminoundecanoate 是一种属于 PEG 类的 PROTAC linker。它可用于合成一系列 PROTAC 分子。
T17638	Boc-11-aminoundecanoic acid	Others; PROTAC Linker	Others; PROTAC
	Boc-11-aminoundecanoic acid 是一种属于 Alkyl/ether 类的 PROTAC linker，可用于 MS432 的合成。
T18487	NH2-C6-NH-Boc	Others; PROTAC Linker	Others; PROTAC
	NH2-C6-NH-Boc 是一种属于 alkyl/ether 类的 PROTAC linker ，是基于 PROTAC 技术的 Mcl-1 抑制剂。
T14408	Azido-PEG1-CH2CO2H 4-哌啶酮缩乙二醇	Others; PROTAC Linker	Others; PROTAC
	Azido-PEG1-CH2CO2H 是属于 alkyl/ether 类的PROTAC linker，可用于合成 PROTAC BRD4 Degrader-1.
T18151	m-PEG16-alcohol 十六乙二醇单甲醚	Others; PROTAC Linker	Others; PROTAC
	m-PEG16-alcohol 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T14413	Azido-PEG10-alcohol 叠氮-十聚乙二醇	Others; PROTAC Linker	Others; PROTAC
	Azido-PEG10-alcohol 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T15976	Mal-PEG1-NHS ester	Others; PROTAC Linker	Others; PROTAC
	Mal-PEG1-NHS ester 是一种可裂解的基于 PEG 的 ADC 接头，用于合成抗体-药物偶联物。它也是基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。
T17482	Azido-PEG11-alcohol 叠氮-十一聚乙二醇	Others; PROTAC Linker	Others; PROTAC
	Azido-PEG11-alcohol 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T17694	Br-C10-methyl ester 11-溴代十一烷酸甲酯	Others; PROTAC Linker	Others; PROTAC
	Br-C10-methyl ester 是一种属于 alkyl/ether 类的 PROTAC linker，可用于一系列 PROTAC 分子的合成。PROTAC 分子含有两个通过 linker 连接的不同配体，一种是 VHL 配体部分，另一种是靶蛋白配体。
T18485	NH2-C4-NH-Boc N-叔丁氧羰基-1,4-丁二胺	Others; PROTAC Linker	Others; PROTAC
	NH2-C4-NH-Boc 是一种属于 Alkyl/ether 类的 PROTAC linker，可用于一系列 PROTAC 分子的合成。
T18391	N-Boc-4-pentyne-1-amine	Others; PROTAC Linker	Others; PROTAC
	N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound utilized in the synthesis of PROTAC MG-277[1].
T10359	AR antagonist 1	Androgen Receptor; Ligand for E3 Ligase; Ligands for Target Protein for PROTAC	Endocrinology/Hormones; PROTAC
	AR antagonist 1 是 AR 拮抗剂，能够与 E3 连接酶配体结合，与 VHL 蛋白结合亲和力较弱，用于 PROTACARD-266 合成。
T18143	m-PEG12-OH Dodecaethylene Glycol Monomethyl Ether	Others; PROTAC Linker	Others; PROTAC
	m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) 是一种基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。它也是一种不可切割的 12 单元 PEG ADC 接头，用于合成抗体-药物偶联物。
T18807	Thalidomide-NH-C4-NH-Boc	E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase	PROTAC
	Thalidomide-NH-C4-NH-Boc 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T14591	Biotin-PEG3-azide N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺	Others; PROTAC Linker	Others; PROTAC
	Biotin-PEG3-azide 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成
T16665	Triethylene glycol PROTAC Linker 25	Others	Others
	Triethylene glycol (PROTAC Linker 25) is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T16312	NH2-PEG3 PROTAC Linker 35	Others	Others
	NH2-PEG3 (PROTAC Linker 35) is a polyethylene glycol (PEG) linker utilized in the synthesis of PROTAC (β-NF-JQ1)[1].
T16658	Boc-NH-PEG4 PROTAC Linker 12	Others	Others
	Boc-NH-PEG4, also known as PROTAC Linker 12, is a PEG-based linker compound utilized for the synthesis of PROTACs[1].
T16657	Boc-NH-PEG2 PROTAC Linker 11	Others	Others
	Boc-NH-PEG2 (PROTAC Linker 11) is a polyethylene glycol (PEG)-based linker that finds application in the synthesis of PROTACs. [1]
T18620	Tos-PEG2-NH2 PROTAC Linker 27	Others	Others
	Tos-PEG2-NH2 (PROTAC Linker 27) is a Polyethylene Glycol (PEG)-based linker used for the synthesis of Proteolysis-Targeting Chimeras (PROTACs)[1].
T16662	Tetraethylene glycol PROTAC Linker 18,三缩四乙二醇	Others	Others
	Tetraethylene glycol (PROTAC Linker 18) is a polyethylene glycol (PEG)-based linker that finds utility in the synthesis of PROTACs[1].
T16660	N3-PEG3-CH2COOH PROTAC Linker 14	Others	Others
	N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based compound utilized for the synthesis of PROTACs.
T14642	Bis-PEG5-acid PROTAC Linker 36	Others	Others
	Bis-PEG5-acid (PROTAC Linker 36) is a polyethylene glycol (PEG) linker employed for the synthesis of CP5V, a PROTAC that selectively degrades Cdc20[1].
T16663	Bis-NH2-PEG2 PROTAC Linker 19	Others	Others
	Bis-NH2-PEG2 (PROTAC Linker 19) is a PEG-based linker compound utilized for the synthesis of PROTACs.
T16664	N3-PEG4-C2-NH2 PROTAC Linker 20	Others	Others
	N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based linker compound utilized for the synthesis of PROTACs. Its chemical structure enables efficient conjugation and serves as a bridging element between the target protein and the E3 ligase, facilitating targeted protein degradation[1].
T18621	Tos-PEG1-O-CH2COOH PROTAC Linker 28	Others	Others
	Tos-PEG1-O-CH2COOH (PROTAC Linker 28), a PEG-based PROTAC linker, finds applicability in PROTACs synthesis [1].
T18628	Tos-PEG4-NH-Boc PROTAC Linker 7	Others	Others
	Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker used for the synthesis of PROTACs[1].
T18618	Bis-NH2-C1-PEG3 PROTAC Linker 24	Others	Others
	Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs. This compound serves as a critical component in constructing PROTAC molecules, facilitating the targeted degradation of specific proteins[1].
T16666	NH2-PEG3-C1-Boc PROTAC Linker 5	Others	Others
	NH2-PEG3-C1-Boc, also known as PROTAC Linker 5, is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T18630	Tos-PEG3-NH-Boc PROTAC Linker 9	Others	Others
	Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based linker utilized for the synthesis of PROTACs. It plays a critical role in facilitating the connection between a target protein and an E3 ubiquitin ligase, ultimately leading to the degradation of the target protein.
T18626	Dox-Ph-PEG1-Cl PROTAC Linker 34	Others	Others
	Dox-Ph-PEG1-Cl, also referred to as PROTAC Linker 34, is a PEG-based compound employed for the synthesis of PROTACs[1].
T16661	NH2-PEG5-C2-NH-Boc PROTAC Linker 17	Others	Others
	NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based compound utilized as a linker in the synthesis of PROTACs[1].
T18627	Tos-PEG3-O-C1-CH3COO PROTAC Linker 6	Others	Others
	Tos-PEG3-O-C1-CH3COO (PROTAC Linker 6) is a PEG-based linker compound that finds utility in the synthesis of PROTACs[1].
T18619	Bis-PEG1-C-PEG1-CH2COOH PROTAC Linker 26	Others	Others
	Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) is a PEG-based linker suitable for the synthesis of PROTACs, compound complexes that selectively degrade target proteins[1].
T18637	Boc-C1-PEG2-C4-Cl PROTAC Linker 1	Others	Others
	Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound utilized for the synthesis of PROTACs. This chemical compound serves as a linker in the development of PROTACs[1].
T16659	Boc-NH-PEG2-C2-NH2 PROTAC Linker 13	Others	Others
	Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based linker utilized for the synthesis of PROTACs. This chemical compound plays a crucial role in connecting the targeted protein and the E3 ubiquitin ligase for selective protein degradation[1].
T18615	Phenol-amido-C1-PEG3-N3 PROTAC Linker 21	Others	Others
	Phenol-amido-C1-PEG3-N3, also known as PROTAC Linker 21, is a PEG-based linker utilized for synthesizing PROTACs.
T18625	Boc-NH-C6-amido-C4-acid PROTAC Linker 32	Others	Others
	Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based linker extensively employed in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T18624	NH2-Ph-C4-acid-NH2-Me PROTAC Linker 31	Others	Others
	NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1]
T18623	Boc-NH-PEG2-C2-amido-C4-acid PROTAC Linker 30	Others	Others
	Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T17881	(S,R,S)-AHPC-C10-NH2 VH032-C10-NH2	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) 包含基于 (S,R,S)-AHPC 的VHL 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)。用于 BET 的靶向 PROTAC 的合成。
T15529	Hydroxy-PEG4-(CH2)2-Boc 丙酸叔丁酯-四聚乙二醇	PROTAC Linker	PROTAC
	Hydroxy-PEG4-(CH2)2-Boc 是一种不可切割的 ADC 接头，用于合成抗体-药物偶联物。它也可用作 PROTAC 接头用于 PROTAC 合成。.
T18638	Boc-C5-O-C5-O-C6-Cl PROTAC Linker 2	Others	Others
	Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a chemical compound commonly employed as a linker in PROTAC applications. Its primary function is to connect a specific tyrosine kinase inhibitor (TKI) with the E3 recruiting ligand.

化合物

Cl-C6-PEG4-O-CH2COOH

Cat.No: T18639

Synonym: PROTAC Linker 4

Target: Others

Cat.No: T18629

Synonym: PROTAC Linker 8,三聚乙二醇-乙酸

Target: Others, PROTAC Linker

Cat.No: T18616

Synonym: PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺

Target: Others, PROTAC Linker

Cat.No: T18617

Synonym: N-(5-氨基戊基)氨基甲酸叔丁酯,PROTAC Linker 23

Target: Others, PROTAC Linker

Cat.No: T7701

Synonym: PROTAC Linker 10,2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇

Target: Others, PROTAC Linker

Cat.No: T18614

Synonym: Tetraethylene glycol di(p-toluenesulfonate),PROTAC Linker 16,1,11-Bis(tosyloxy)-3,6,9-trioxaundecane

Target: Others, PROTAC Linker

Monoethyl pimelate

Cat.No: T18363

Target: Others, PROTAC Linker

tert-Butyl 11-aminoundecanoate

Cat.No: T18788

Target: PROTAC Linker

Boc-11-aminoundecanoic acid

Cat.No: T17638

Target: Others, PROTAC Linker

Cat.No: T18487

Target: Others, PROTAC Linker

Azido-PEG1-CH2CO2H

Cat.No: T14408

Synonym: 4-哌啶酮缩乙二醇

Target: Others, PROTAC Linker

m-PEG16-alcohol

Cat.No: T18151

Synonym: 十六乙二醇单甲醚

Target: Others, PROTAC Linker

Azido-PEG10-alcohol

Cat.No: T14413

Synonym: 叠氮-十聚乙二醇

Target: Others, PROTAC Linker

Mal-PEG1-NHS ester

Cat.No: T15976

Target: Others, PROTAC Linker

Azido-PEG11-alcohol

Cat.No: T17482

Synonym: 叠氮-十一聚乙二醇

Target: Others, PROTAC Linker

Br-C10-methyl ester

Cat.No: T17694

Synonym: 11-溴代十一烷酸甲酯

Target: Others, PROTAC Linker

Cat.No: T18485

Synonym: N-叔丁氧羰基-1,4-丁二胺

Target: Others, PROTAC Linker

N-Boc-4-pentyne-1-amine

Cat.No: T18391

Target: Others, PROTAC Linker

AR antagonist 1

Cat.No: T10359

Target: Androgen Receptor, Ligand for E3 Ligase, Ligands for Target Protein for PROTAC

Cat.No: T18143

Synonym: Dodecaethylene Glycol Monomethyl Ether

Target: Others, PROTAC Linker

Thalidomide-NH-C4-NH-Boc

Cat.No: T18807

Target: E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase

Biotin-PEG3-azide

Cat.No: T14591

Synonym: N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺

Target: Others, PROTAC Linker

Triethylene glycol

Cat.No: T16665

Synonym: PROTAC Linker 25

Target: Others

Cat.No: T16312

Synonym: PROTAC Linker 35

Target: Others

Cat.No: T16658

Synonym: PROTAC Linker 12

Target: Others

Cat.No: T16657

Synonym: PROTAC Linker 11

Target: Others

Cat.No: T18620

Synonym: PROTAC Linker 27

Target: Others

Tetraethylene glycol

Cat.No: T16662

Synonym: PROTAC Linker 18,三缩四乙二醇

Target: Others

N3-PEG3-CH2COOH

Cat.No: T16660

Synonym: PROTAC Linker 14

Target: Others

Cat.No: T14642

Synonym: PROTAC Linker 36

Target: Others

Cat.No: T16663

Synonym: PROTAC Linker 19

Target: Others

Cat.No: T16664

Synonym: PROTAC Linker 20

Target: Others

Tos-PEG1-O-CH2COOH

Cat.No: T18621

Synonym: PROTAC Linker 28

Target: Others

Tos-PEG4-NH-Boc

Cat.No: T18628

Synonym: PROTAC Linker 7

Target: Others

Bis-NH2-C1-PEG3

Cat.No: T18618

Synonym: PROTAC Linker 24

Target: Others

NH2-PEG3-C1-Boc

Cat.No: T16666

Synonym: PROTAC Linker 5

Target: Others

Tos-PEG3-NH-Boc

Cat.No: T18630

Synonym: PROTAC Linker 9

Target: Others

Cat.No: T18626

Synonym: PROTAC Linker 34

Target: Others

NH2-PEG5-C2-NH-Boc

Cat.No: T16661

Synonym: PROTAC Linker 17

Target: Others

Tos-PEG3-O-C1-CH3COO

Cat.No: T18627

Synonym: PROTAC Linker 6

Target: Others

Bis-PEG1-C-PEG1-CH2COOH

Cat.No: T18619

Synonym: PROTAC Linker 26

Target: Others

Boc-C1-PEG2-C4-Cl

Cat.No: T18637

Synonym: PROTAC Linker 1

Target: Others

Boc-NH-PEG2-C2-NH2

Cat.No: T16659

Synonym: PROTAC Linker 13

Target: Others

Phenol-amido-C1-PEG3-N3

Cat.No: T18615

Synonym: PROTAC Linker 21

Target: Others

Boc-NH-C6-amido-C4-acid

Cat.No: T18625

Synonym: PROTAC Linker 32

Target: Others

NH2-Ph-C4-acid-NH2-Me

Cat.No: T18624

Synonym: PROTAC Linker 31

Target: Others

Boc-NH-PEG2-C2-amido-C4-acid

Cat.No: T18623

Synonym: PROTAC Linker 30

Target: Others

(S,R,S)-AHPC-C10-NH2

Cat.No: T17881

Synonym: VH032-C10-NH2

Target: Others, Ligand for E3 Ligase

Hydroxy-PEG4-(CH2)2-Boc

Cat.No: T15529

Synonym: 丙酸叔丁酯-四聚乙二醇

Target: PROTAC Linker

Boc-C5-O-C5-O-C6-Cl

Cat.No: T18638

Synonym: PROTAC Linker 2

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T9784	Docosanedioic acid	PROTAC Linker	PROTAC
	Docosanedioic acid 可以作为ADC linker 或PROTAC linker，用于合成抗体偶联药物或合成 PROTAC。

天然产物

Docosanedioic acid

Cat.No: T9784

Target: PROTAC Linker

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